Dr. Martin Rono
Researcher KWTRP

I received my doctorate degree in cell and molecular biology from the University of Strasbourg, France. My research group largely focuses on host-pathogen interactions and the use of molecular biology tools to understand the underlying mechanisms1-11.

In addition, to research I have a keen interest in capacity building through mentoring young scientist and assisted in the development of molecular biology research facilities such as the PUBReC lab in Pwani University. I have received funding for independent research and capacity building and established a network of collaborations both local and internationally.

Selected grant awards

  1. Functional analysis of Plasmodium PHIST proteins as potential antimalarial vaccine targets, (PI), TWAS $17800
  2. Genomic and transcriptional analysis of malaria parasites from controlled human malaria infection of Kenyan adults with varying exposure to malaria (PI), The Royal Society UK, FLAIR fellowship, £224,500
  3. PU Bioresearch Centre (PUBReC) – A Model for enhancing Bioresearch in Local Universities, (PI), NRF Kenya, KES 45,400,000
  4. Understanding residual transmission for sustainable malaria control and enhancement of elimination efforts in Africa (C0-PI), WHO-TDR, $219,000
  5. Evaluation of the effectiveness of ivermectin co-formulation vs. albendazole for treatment of soil transmitted helminth infections, (C0-PI) EDCTP, €4,900,000

Selected publications 2018-2020

  1. Munyao, V. et al. Surveillance of Culicine Mosquitoes in Six Villages of Taita-Taveta County, Kenya, With Host Determinations From Blood-Fed Females. J Med Entomol, doi:10.1093/jme/tjaa109 (2020).
  2. Karisa, J. et al. Urban Ecology of Arboviral Mosquito Vectors Along the Kenyan Coast. J Med Entomol, doi:10.1093/jme/tjaa136 (2020).
  3. Kabaka, J. M. et al. Expansions of chemosensory gene orthologs among selected tsetse fly species and their expressions in Glossina morsitans morsitans tsetse fly. PLoS Negl Trop Dis 14, e0008341, doi:10.1371/journal.pntd.0008341 (2020).
  4. Rono, M. K. et al. Cadmium tolerance pathway in Anopheles gambiae senso stricto. Acta Trop 198, 105033, doi:10.1016/j.actatropica.2019.05.024 (2019).
  5. Musimbi, Z. D. et al. Peripheral blood mononuclear cell transcriptomes reveal an over-representation of downregulated genes associated with immunity in HIV-exposed uninfected infants. Sci Rep 9, 18124, doi:10.1038/s41598-019-54083-4 (2019).
  6. Mang’era, C. M. et al. Growth-disrupting Murraya koenigii leaf extracts on Anopheles gambiae larvae and identification of associated candidate bioactive constituents. Acta Trop 190, 304-311, doi:10.1016/j.actatropica.2018.12.009 (2019).
  7. Khamis, F. M. et al. Species-specific transcriptional profiles of the gut and gut microbiome of Ceratitis quilicii and Ceratitis rosa sensu stricto. Sci Rep 9, 18355, doi:10.1038/s41598-019-54989-z (2019).
  8. Gildenhard, M. et al. Mosquito microevolution drives Plasmodium falciparum dynamics. Nat Microbiol 4, 941- 947, doi:10.1038/s41564-019-0414-9 (2019).
  9. Simam, J. et al. Gene copy number variation in natural populations of Plasmodium falciparum in Eastern Africa. BMC Genomics 19, 372, doi:10.1186/s12864-018-4689-7 (2018).
  10. Rono, M. K. et al. Adaptation of Plasmodium falciparum to its transmission environment. Nat Ecol Evol 2, 377- 387, doi:10.1038/s41559-017-0419-9 (2018).
  11. Bamou, R. et al. Changes in malaria vector bionomics and transmission patterns in the equatorial forest region of Cameroon between 2000 and 2017. Parasit Vectors 11, 464, doi:10.1186/s13071-018-3049-4 (2018).